A Letter from CABS, about Coronavirus Outbreak

Date: January 27, 2020 @ 12:00 am – February 29, 2020
Location:

About current Coronavirus outbreak, what CABS can do?

Dear CABS community:

I believe everyone is concerned about the novel Coronavirus (2019-nCov) outbreak in Wuhan, China. CABS is no difference. CABS Executive Council team has been closely monitoring the situation and actively discussing what we can help. Here are a few things we want to share with you. 

1. Dose CABS accept donations to buy critical medical supplies for China?

Currently CABS doesn't accept donations for the purpose of buying critical medical supplies for China. This is because most of the critical items, e.g., medical face masks and protection clothes, are out of stock for most US distributors and manufacturers. Major manufacturers will ramp up production in China and distribute directly in China. There is very limited supply in the US that we can buy. We have confirmed that many sister organizations are facing similar challenges. CABS will closely monitor the situation and update our community when we are ready to accept donations for relieving 2019-nCov outbreak. 

2. What is the plan for upcoming CABS events?

Public health and safety is always the first priority for CABS events. We have cancelled CABS Chinese New Year Party that was planned on Jan. 26th. We also postponed all upcoming CABS events in February and March. CABS will closely monitor the situation and update our next event schedule through our website and weekly newsletter.

3. What is CABS recommendation on prevention of 2019-nCov infection?

CABS recommends everyone to get the latest updates and guidance from US CDC website (https://www.cdc.gov/coronavirus/2019-ncov/index.html). 

A. CDC guidance in English: https://www.cdc.gov/coronavirus/2019-ncov/guidance-prevent-spread.html

B. CDC guidance in Chinese: https://www.cdc.gov/coronavirus/2019-ncov/guidance-prevent-spread-chinese.html

C. CDC guidance on traveling to China: https://wwwnc.cdc.gov/travel/notices/warning/novel-coronavirus-wuhan-china

4. CABS is recruiting volunteers to write scientific/educational articles on discovery and development of medicines for the prevention and treatment of Coronavirus infection.

Most of CABS members are professionals in drug discovery industry. This is where we can help. We are looking for volunteers to write short scientific articles (1-3 pages with figures/tables and text) on the following topics. The articles will be shared with CABS community by weekly newsletter and WeChat. We hope this effort could advocate more discovery efforts on potential therapeutics for Coronavirus.

A. Discovery of Coronavirus entry inhibitors (antibody, peptides, purified proteins or small molecules)

B. Discovery of Coronavirus protease inhibitors

C. Discovery of Coronavirus RNA polymerase inhibitors

D. Discovery of Coronavirus assembly and secretion inhibitors

E. siRNA for Coronavirus

F. Immunotherapy for Coronavirus (vaccine and others)

G. Diagnostics for Coronavirus

H. In vitro screening for inhibitors of Coronavirus

If you are interested in writing scientific articles on above topics or you have additional topics/ideas, please email yang.tian@cabsweb.org for details. 

CABS is together with all of you, to contribute our efforts curbing Coronavirus outbreak!

Please feel free to email us any other question and suggestion: info@cabsweb.org

Sincerely

Yang Tian

CABS President

关于当前的新冠状病毒爆发，CABS能做什么？

尊敬的CABS社区：

我相信每个人都对在中国武汉爆发的新型冠状病毒（2019-nCov）感到担忧。 CABS也和你们一样。 CABS执行理事会团队一直密切关注局势的发展，并积极探讨我们可以提供的帮助。在此，我们想与您分享一些目前的想法及计划。

一. CABS是否接受捐款用于为中国购买必要的医疗用品？

目前，CABS不接受用于为中国购买必要医疗用品的捐款。原因是来自大多数美国分销商和制造商的必要医疗用品（例如医用口罩和防护服）目前都缺货。而且，目前的趋势是这些医疗用品的主要制造商将提高在中国的产量，并直接在中国分销。在美国，我们可以购买的货源非常有限。我们已经和许多姊妹组织确认，他们都面临着类似的挑战。CABS将密切关注局势的发展，并根据情况更新和调整是否需要大家的捐款来缓解2019-nCov疫情。

二. CABS对将举行的活动有什么计划？

公共卫生与安全始终是CABS活动中优选考虑的第一要素。为此，我们已取消原定于1月26日举行的CABS农历新年晚会。我们还推迟了CABS在2月和3月份的活动。 CABS将密切关注局势的发展，并通过我们的网站和每周新闻通讯更新我们的下一个活动时间表。

三. CABS对预防2019-nCov感染有什么建议？

CABS建议大家从美国疾病预防控制中心网站获取最新更新和指南（https://www.cdc.gov/coronavirus/2019-ncov/index.html）。

A. CDC英文指南：https://www.cdc.gov/coronavirus/2019-ncov/guidance-prevent-spread.html

B. CDC中文指南：https://www.cdc.gov/coronavirus/2019-ncov/guidance-prevent-spread-chinese.html

C. CDC对前往中国旅游的指南：https://wwwnc.cdc.gov/travel/notices/warning/novel-coronavirus-wuhan-china

四．CABS正在招募志愿者撰写与开发用于预防和治疗冠状病毒感染的药物相关的科普和教育类文章。

CABS的大多数成员是药物研发的专业人员，这是我们的优势也是我们最可以提供帮助的地方。我们正在寻找志愿者撰写以下主题的简短科普文章（包括图表和文字共1-3页）。这些文章将通过网站、每周新闻通讯和微信公众号与CABS社区共享。我们希望这项工作有助于对冠状病毒的潜在疗法有更多的发现。

A. 冠状病毒侵染宿主细胞的抑制剂（抗体、多肽、纯化蛋白质或小分子）

B. 冠状病毒蛋白酶抑制剂

C. 冠状病毒RNA聚合酶抑制剂

D. 冠状病毒装配和分泌抑制剂

E. 针对冠状病毒的siRNA

F. 冠状病毒的免疫疗法（疫苗和其它）

G. 冠状病毒的诊断

H. 冠状病毒药物体外筛选模型的建立和使用

如果您有兴趣撰写有关上述主题的科普文章，或者您有其它主题/想法，请发送电子邮件至yang.tian@cabsweb.org。

CABS和大家一起，为遏制冠状病毒的爆发做出我们最大的努力！ 如果您有其它任何问题和建议，请发送邮件至：info@cabsweb.org。

谢谢！

田洋博士

CABS会长