Senior Scientist I, Tumor Biology (Cancer Signaling)

Company:   Exelixis
Location:  Alameda, CA
Posted:  2019-06-28

SUMMARY: The Senior Scientist I, Tumor Biology (Cancer Signaling) will have broad knowledge in cancer biological signaling pathways. The successful candidate will be responsible for leading cutting-edge research programs, and will leverage their deep insights and understanding of cellular and molecular pathway mechanisms that drive cancer development and progression to advance drug discovery programs. The individual will also be responsible for identifying new technologies and for implementing these technologies to advance drug candidates from concept to clinical proof-of-mechanism. This role supports the oncology pipeline by working with the Associate Director of Tumor Biology on overall research projects, establishing decision-making cascades, aligning on go/no-go decisions, timelines and resourcing required for success. ESSENTIAL DUTIES AND RESPONSIBILITIES: • Designs, plans and leads oncology research projects focused on the targeting and interrogation of cancer signaling pathways with a deep knowledge of cutting-edge approaches focused on tumor biology for cancer therapy. • Serves as a senior research staff member to provide research guidance and project leadership in identifying, advancing, and supporting internal and external research collaborations in developing novel cancer therapies. • Develops, evaluates, optimizes and implements new technologies, laboratory protocols, and methodologies for cell-based assays. • Keeps up-to-date with relevant scientific advancements, competitive landscape, and new technologies, relevant to the research projects. • Presents data and reports on project status to department head and at company research meetings, and communicates scientific results to corporate partners and/or collaborators. • Interacts and collaborates with internal groups and departments to discuss and resolve program and/or department needs. • Maintains laboratory notebook in a complete, consistent and concise manner in accordance with company intellectual property policies and practices. • Complies with company health and safety policies and general laboratory practices. SUPERVISORY RESPONSIBILITIES: • Directly supervises a team of research associates and scientists EDUCATION/EXPERIENCE/KNOWLEDGE: Education: • Ph.D. in cancer biology or related field with post-doctoral experience • A minimum of 6 years drug discovery experience after completion of post-doctoral training EXPERIENCE: • Experience managing projects and/or workgroups in biotechnology or pharmaceutical organizations including experience with management/coaching of employees. • Established strong publication track record in oncology drug discovery research • Ability to collaborate effectively cross-functionally and in a team setting • Ability to multi-task in a fast-paced dynamic environment while delivering high quality work SPECIFIC KNOWLEDGE: • Experience working with cutting edge in vitro and ex vivo cell-based assay systems • Broad understanding of cancer signaling pathways and methods for interrogating these pathways • Sets goals with understanding of priority and impact to the program, department and organization. • Applies advanced scientific and technical principles, theories and concepts. Contributes to the development of new principles and concepts. ORAL AND WRITTEN COMMUNICATION: • Ability to read, analyze and interpret common scientific and technical journals, financial reports and legal documents. • Excellent interpersonal and written communication skills JOB COMPLEXITY: • Works on extremely complex problems where analysis of situations or data requires an evaluation of intangible variables. • Exercises independent judgment in developing methods, techniques and evaluation criteria for obtaining results. • Uses professional concepts to contribute to development of company’s concepts and principles and to achieve objectives in creative and effective ways. SUPERVISION RECEIVED: • Acts independently to determine methods and procedures on new assignments and may provide guidance and oversee the activities of other lower level personnel DISCRETION: • Erroneous decisions or failure to achieve goals may result in additional costs and personnel, and serious delays in overall schedule STATUS: • This job is exempt. DISCLAIMER The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

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